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IOD2 Polyclonal Antibody, 100ul Antibody Development Dentatorubral pallidoluysian atrophy (DRPLA) is

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SEK123.75 SEK160.75

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IOD2 Polyclonal Antibody, 100ul Antibody Development Dentatorubral pallidoluysian atrophy (DRPLA) isThe protein encoded by this gene belongs to the iodothyronine deiodinase family. It catalyzes the conversion of prohormone thyroxine (3,5,3',5' tetraiodothyronine, T4) to the bioactive thyroid hormone (3,5,3' triiodothyronine, T3) by outer ring 5' deiodination. This gene is widely expressed, including in thyroid, placenta, pituitary and brain. It is thought to be responsible for the 'local' production of T3, and thus important in influencing thyroid

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Description

Dentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia

As many as six of this type II cytokeratin (KRT6) have been identified

It binds to the chemokine (C-C motif) receptor 8

which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP

IOD2 Polyclonal Antibody, 100ul Antibody Development Dentatorubral pallidoluysian atrophy (DRPLA) isThe protein encoded by this gene belongs to the iodothyronine deiodinase family. It catalyzes the conversion of prohormone thyroxine (3,5,3',5' tetraiodothyronine, T4) to the bioactive thyroid hormone (3,5,3' triiodothyronine, T3) by outer ring 5' deiodination. This gene is widely expressed, including in thyroid, placenta, pituitary and brain. It is thought to be responsible for the 'local' production of T3, and thus important in influencing thyroid

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