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Integrin Alpha3 Polyclonal Antibody, 100ul[BT-AP04572] PCR Series The native protein binds specifically

SKU: 62280819898

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Integrin Alpha3 Polyclonal Antibody, 100ul[BT-AP04572] PCR Series The native protein binds specificallyITGA2 encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The integrin subunit alpha 2 forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia.

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Description

The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1

Homeobox protein Hox-A7 represses the transcription of differentiation-specific genes during keratinocyte proliferation

Dipeptidyl peptidase 2 encoded by DPP7 is a post-proline cleaving aminopeptidase expressed in quiescent lymphocytes

and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance

Integrin Alpha3 Polyclonal Antibody, 100ul[BT-AP04572] PCR Series The native protein binds specificallyITGA2 encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The integrin subunit alpha 2 forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia.

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