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Lymphotactin Polyclonal Antibody, 20ul[BT-AP05123] Peptide Modification KNG1 uses alternative splicing to

SKU: 62354248798

4.5
PLN97.20 PLN136.20

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Lymphotactin Polyclonal Antibody, 20ul[BT-AP05123] Peptide Modification KNG1 uses alternative splicing toXCL1 encodes a member of the chemokine superfamily. Chemokines function in inflammatory and immunological responses, inducing leukocyte migration and activation. The encoded protein is a member of the C chemokine subfamily, retaining only two of four cysteines conserved in other chemokines, and is thought to be specifically chemotactic for T cells. This gene and a closely related family member are located on the long arm of chromosome 1.

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Description

KNG1 uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK)

the increase in capillary permeability due to contraction of terminal venules

AZI1 contains one IQ domain

Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway

Lymphotactin Polyclonal Antibody, 20ul[BT-AP05123] Peptide Modification KNG1 uses alternative splicing toXCL1 encodes a member of the chemokine superfamily. Chemokines function in inflammatory and immunological responses, inducing leukocyte migration and activation. The encoded protein is a member of the C chemokine subfamily, retaining only two of four cysteines conserved in other chemokines, and is thought to be specifically chemotactic for T cells. This gene and a closely related family member are located on the long arm of chromosome 1.

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