Phospho-ATR (S428) Polyclonal Antibody, 50ul Multi-Layer Cell Culture System The ubiquitin (Ub) pathway involves
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Phospho-ATR (S428) Polyclonal Antibody, 50ul Multi-Layer Cell Culture System The ubiquitin (Ub) pathway involvesThe protein encoded by ATR (ATR serine threonine kinase) belongs the PI3 PI4 kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1,
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