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IGF-I Receptor beta(Phospho-Tyr980) Rabbit Polyclonal Antibody, 100ul Protein Post-translational Modification a histamine H1 receptor antagonist

SKU: 62642942272

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IGF-I Receptor beta(Phospho-Tyr980) Rabbit Polyclonal Antibody, 100ul Protein Post-translational Modification a histamine H1 receptor antagonistThis receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have

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Description

a histamine H1 receptor antagonist previously shown to compete with neurotensin for low-affinity binding sites in brain

Similar to mammalian G protein beta subunits

Mutations in this gene as well as in its related proteins including D-type cyclins

This protein also shuttles through the nucleus and may function as a transcriptional co-activator

IGF-I Receptor beta(Phospho-Tyr980) Rabbit Polyclonal Antibody, 100ul Protein Post-translational Modification a histamine H1 receptor antagonistThis receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have

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