CKAP2 Rabbit Polyclonal Antibody, 50ul Immune Cell Analysis Differential and in situ hybridization

Differential and in situ hybridization studies indicate that this lectin is specifically expressed in keratinocytes and found mainly in stratified squamous epithelium

Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways

The encoded protein functions as a homodimer and requires divalent cations for ligand binding

Their transcriptional activity is repressed by an intervening inhibitory domain (ID)

CKAP2 Rabbit Polyclonal Antibody, 50ul Immune Cell Analysis Differential and in situ hybridizationThis gene encodes a cytoskeleton associated protein that stabalizes microtubules and plays a role in the regulation of cell division. The encoded protein is itself regulated through phosphorylation at multiple serine and threonine residues. There is a pseudogene of this gene on chromosome 14. Alternative splicing results in multiple transcript variations.