Smad2/3 Polyclonal Antibody, 100ul Centrifuges The EGF containing fibulin like

The EGF containing fibulin like extracellular matrix protein 2 encoded by EFEMP2 contains four EGF2 domains and six calcium-binding EGF2 domains

The encoded protein binds an iron/sulfur cluster and may be involved in calcium homeostasis

This gene is located on chromosome 17 in the same region as a retinal gene which is mutated in progressive rod-cone degeneration

suggesting a role in peroxisome organization and biogenesis

Smad2/3 Polyclonal Antibody, 100ul Centrifuges The EGF containing fibulin likeMothers against decapentaplegic homolog 2 encoded by SMAD2 belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF) beta, and thus regulates multiple cellular