PSME1 Rabbit Polyclonal Antibody, 20ul Enzymes Regulates lipopolysaccharide-induced IL-12 synthesis in

Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6

A similar protein in Rat appears to bind the large subunit of RNA polymerase II and provide a link between transcription and pre-mRNA splicing

The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors| including estrogen receptor alpha| nuclear respiratory factor 1| and glucocorticoid receptor

which determines the substrate specificity of the complex

PSME1 Rabbit Polyclonal Antibody, 20ul Enzymes Regulates lipopolysaccharide-induced IL-12 synthesis inThe 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base which contains 6 ATPase subunits and 2 non ATPase subunits and a lid which contains up to 10 non ATPase subunits.