TTR mouse Monoclonal Antibody(2B12), 20ul Pathway and Network Analysis DnaJ heat shock protein family

DnaJ heat shock protein family (Hsp40) member B4encoded by DNAJB4 is a molecular chaperone

is the human homolog of the yeast ELO3 protein

Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome

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TTR mouse Monoclonal Antibody(2B12), 20ul Pathway and Network Analysis DnaJ heat shock protein familyThis gene encodes transthyretin, one of the three prealbumins including alpha 1 antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported most mutations are related to amyloid