EI2BE Polyclonal Antibody, 100ul Pasteur Pipets DM plays a central role

DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site

This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen

and facilitating tissue invasion

The mediator complex subunit 8 may also function in ubiquitin ligation and protein degradation

EI2BE Polyclonal Antibody, 100ul Pasteur Pipets DM plays a central roleThis gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.