MB211 Rabbit Polyclonal Antibody, 50ul Pipette Filler Non-receptor tyrosine-protein kinase TYK2 associates

Non-receptor tyrosine-protein kinase TYK2 associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits

Members of this superfamily are often drug targets for treating diseases

Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis

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MB211 Rabbit Polyclonal Antibody, 50ul Pipette Filler Non-receptor tyrosine-protein kinase TYK2 associatesThis gene is similar to the MAB 21 cell fate determining gene found in C. elegans. It may be involved in eye and cerebellum development and it has been proposed that expansion of a trinucleotide repeat region in the 5' UTR may play a role in a variety of psychiatric disorders.