DCAMKL2 Polyclonal Antibody, 100ul Endonucleases & Exonucleases The encoded protein may act

The encoded protein may act as a transcriptional activator

The flamingo cadherins consist of nonclassic-type cadherins that do not interact with catenins

Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function (PMID: 19956863

possibly as a result of compromised regulatory T cell recruitment

DCAMKL2 Polyclonal Antibody, 100ul Endonucleases & Exonucleases The encoded protein may actDCLK2 encodes a member of the protein kinase superfamily and the doublecortin family. Doublecortin like kinase 2 encoded by DCLK2 contains two N terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C terminal serine threonine protein kinase domain, which shows substantial homology to Ca2+ calmodulin dependent protein kinase, and a serine proline rich domain in between the doublecortin and the protein kinase