FoxO1/3/4 Polyclonal Antibody, 50ul Digital Burette The N-terminal half of this

The N-terminal half of this protein contains 10 copies of leu-gly-asn (LGN) repeat

Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs

some of which are associated with Creutzfeldt-Jakob disease

Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified

FoxO1/3/4 Polyclonal Antibody, 50ul Digital Burette The N-terminal half of thisFOXO1 belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.