BRWD3 Polyclonal Antibody, 100ul Monoclonal Antibody Preparation The protein encoded by PDX1

The protein encoded by PDX1 is a transcriptional activator of several genes

May contribute to regulation of the immune system

The encoded protein may function as a transcriptional repressor and play a role in adipogenesis and smooth muscle cell differentiation

alternate transcriptional splice variants

BRWD3 Polyclonal Antibody, 100ul Monoclonal Antibody Preparation The protein encoded by PDX1The bromodomain and WD repeat domain containing 3 encoded by BRWD3 contains a bromodomain and several WD repeats. It is thought to have a chromatin modifying function, and may thus play a role in transcription. Mutations in this gene cause mental retardation X linked type 93, which is also referred to as mental retardation X linked with macrocephaly. This gene is also associated with translocations in patients with B cell chronic lymphocytic leukemia.