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Glucuronidase Beta Polyclonal Antibody, 20ul Cell Culture Dishes Overexpression of this gene product

SKU: 65304315691

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Glucuronidase Beta Polyclonal Antibody, 20ul Cell Culture Dishes Overexpression of this gene productGUSB encodes a hydrolase that degrades glycosaminoglycans, including heparan sulfate, dermatan sulfate, and chondroitin 4,6 sulfate. The enzyme forms a homotetramer that is localized to the lysosome. Mutations in this gene result in mucopolysaccharidosis type VII. Alternative splicing results in multiple transcript variants. There are many pseudogenes of this locus in the human genome.

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Description

Overexpression of this gene product may be associated with neoplastic transformation for some tumors

protein kinases

Pseudogenes of CXADR are found on chromosomes 15

CLIP1 is highly expressed in Reed-Sternberg cells of Hodgkin disease

Glucuronidase Beta Polyclonal Antibody, 20ul Cell Culture Dishes Overexpression of this gene productGUSB encodes a hydrolase that degrades glycosaminoglycans, including heparan sulfate, dermatan sulfate, and chondroitin 4,6 sulfate. The enzyme forms a homotetramer that is localized to the lysosome. Mutations in this gene result in mucopolysaccharidosis type VII. Alternative splicing results in multiple transcript variants. There are many pseudogenes of this locus in the human genome.

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