Dok-7 Polyclonal Antibody, 100ul Centrifugal Filter Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding different isoforms exist

surface immunoglobulin (Ig)

The protein encoded by this gene is a cytosolic prolyl endopeptidase that cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long

Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified

Dok-7 Polyclonal Antibody, 100ul Centrifugal Filter Alternatively spliced transcript variants encodingThe docking protein 7 encoded by DOK7 is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle specific receptor kinase. Mutations in DOK7 are a cause of familial limb girdle myasthenia autosomal