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Shc(Phospho Ser36) Polyclonal Antibody, 100ul Adeno-associated Virus Packaging This gene encodes a member

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Shc(Phospho Ser36) Polyclonal Antibody, 100ul Adeno-associated Virus Packaging This gene encodes a memberThis gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2 SOS complex. p66Shc is not involved in Ras activation.

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Description

This gene encodes a member of the SLC29A/ENT transporter protein family

The complex is involved in intracellular transport and motility

The encoded protein has been shown to be involved in development of the nervous system

Pseudogenes of this gene are found on multiple chromosomes

Shc(Phospho Ser36) Polyclonal Antibody, 100ul Adeno-associated Virus Packaging This gene encodes a memberThis gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2 SOS complex. p66Shc is not involved in Ras activation.

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