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PHC3 Polyclonal Antibody, 20ul Peptide Modification TYMP encodes an angiogenic factor

SKU: 65977807046

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PHC3 Polyclonal Antibody, 20ul Peptide Modification TYMP encodes an angiogenic factorComponent of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys 119', rendering chromatin heritably changed in its expressibility.,PTM: Phosphorylated upon DNA damage, probably by ATM or

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Description

TYMP encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells

later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654

A mutation in this gene results in one form of Zellweger syndrome

The GTP-bound form of the encoded protein has been shown to interact with early-endosomal antigen 1

PHC3 Polyclonal Antibody, 20ul Peptide Modification TYMP encodes an angiogenic factorComponent of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys 119', rendering chromatin heritably changed in its expressibility.,PTM: Phosphorylated upon DNA damage, probably by ATM or

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