Endoglin Polyclonal Antibody, 100ul Enzyme Activity Assays |induction:Down-regulated during maturation of dendritic

|induction:Down-regulated during maturation of dendritic cells by selective stimuli such as LPS| CD40L and zymosan

This enzyme is a type II transmembrane protein

Belongs to the reprimo family

The protein encoded by this gene is a cholesterol transporter and is also able to bind and transport other sterol-derived molecules related to the cholesterol/bile acid biosynthetic pathways such as 25-hydroxycholesterol

Endoglin Polyclonal Antibody, 100ul Enzyme Activity Assays |induction:Down-regulated during maturation of dendriticThis gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler Rendu Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be