BRCA2 Polyclonal Antibody, 100ul Antibodies The Mediator complex is a

The Mediator complex is a multi-protein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II

FPR1 encodes a G protein-coupled receptor of mammalian phagocytic cells that is a member of the G-protein coupled receptor 1 family

This gene belongs to the subfamily of piggyBac transposable element derived (PGBD) genes

UBE2D2 encodes a member of the E2 enzyme family

BRCA2 Polyclonal Antibody, 100ul Antibodies The Mediator complex is aInherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is