Phospho-Btk (Y223) Polyclonal Antibody, 50ul NGS Oligos This gene encodes a member

This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases

This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction

Interacts with SV40 large T antigen

Studies suggest two alternately used promoters drive tissue-specific expression

Phospho-Btk (Y223) Polyclonal Antibody, 50ul NGS Oligos This gene encodes a memberBruton tyrosine kinase encoded by BTK plays a crucial role in B cell development. Mutations in BTK cause X linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.