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CHD8 Polyclonal Antibody, 100ul Molecular Weight Markers A mutation in this gene

SKU: 66420251927

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CHD8 Polyclonal Antibody, 100ul Molecular Weight Markers A mutation in this geneThis gene encodes a DNA helicase that functions as a transcription repressor by remodeling chromatin structure. It binds beta catenin and negatively regulates Wnt signaling pathway, which plays a pivotal role in vertebrate early development and morphogenesis. Mice lacking this gene exhibit early embryonic death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Description

A mutation in this gene may be associated with increased risk for Barrett's esophagus and esophageal adenocarcinoma

NBPF1 is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1

tumor-promoting agents

The protein encoded by PTPN6 (protein tyrosine phosphatase

CHD8 Polyclonal Antibody, 100ul Molecular Weight Markers A mutation in this geneThis gene encodes a DNA helicase that functions as a transcription repressor by remodeling chromatin structure. It binds beta catenin and negatively regulates Wnt signaling pathway, which plays a pivotal role in vertebrate early development and morphogenesis. Mice lacking this gene exhibit early embryonic death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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