PHLP1 Polyclonal Antibody, 100ul Cell fragmentation and collection The encoded protein plays a

The encoded protein plays a role in DNA repair and homologous recombination

The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines

Alternative promoter usage and alternate splicing result in multiple variants encoding different isoforms

This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1

PHLP1 Polyclonal Antibody, 100ul Cell fragmentation and collection The encoded protein plays aThis gene encodes a member of the serine threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt mediated insulin signaling.