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p53 (Acetyl Lys370) Polyclonal Antibody, 50ul Transporters Mutations in POLE have been

SKU: 67012102188

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p53 (Acetyl Lys370) Polyclonal Antibody, 50ul Transporters Mutations in POLE have beenTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. Tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome. Alternative

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Description

Mutations in POLE have been associated with colorectal cancer 12 and facial dysmorphism

and 17 spectrin repeats which are involved in dimer formation

They mediate protein-carbohydrate interactions by selectively binding to different sialic acid moieties present on glycolipids and glycoproteins

This gene encodes a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expressed in tissues other than the adrenal cortex and melanocytes

p53 (Acetyl Lys370) Polyclonal Antibody, 50ul Transporters Mutations in POLE have beenTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. Tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome. Alternative

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