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Elf-4 Polyclonal Antibody, 100ul Polyclonal Antibody Preparation Mutations in NPM1 are associated

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Elf-4 Polyclonal Antibody, 100ul Polyclonal Antibody Preparation Mutations in NPM1 are associatedThe E74 like ETS transcription factor 4 encoded by ELF4 is a transcriptional activator that binds and activates the promoters of the CSF2, IL3, IL8, and PRF1 genes. The encoded protein is involved in natural killer cell development and function, innate immunity, and induction of cell cycle arrest in naive CD8+ cells. Two transcript variants encoding the same protein have been found for this gene.

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Description

Mutations in NPM1 are associated with acute myeloid leukemia

2000 [PubMed: 11095983])

and Ifi-203

This protein is predicted to be catalytically inactive

Elf-4 Polyclonal Antibody, 100ul Polyclonal Antibody Preparation Mutations in NPM1 are associatedThe E74 like ETS transcription factor 4 encoded by ELF4 is a transcriptional activator that binds and activates the promoters of the CSF2, IL3, IL8, and PRF1 genes. The encoded protein is involved in natural killer cell development and function, innate immunity, and induction of cell cycle arrest in naive CD8+ cells. Two transcript variants encoding the same protein have been found for this gene.

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