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WFS1 Polyclonal Antibody, 20ul Cell Screening and Imaging Melanoma inhibitory activity (cartilage-derived retinoic

SKU: 6746892857

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WFS1 Polyclonal Antibody, 20ul Cell Screening and Imaging Melanoma inhibitory activity (cartilage-derived retinoicThis gene encodes a transmembrane protein, which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta cell lines. Mutations in this gene are associated with Wolfram syndrome, also called DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness), an autosomal recessive disorder. The disease affects the brain and central nervous system.

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Description

Melanoma inhibitory activity (cartilage-derived retinoic acid-sensitive protein (CD-RAP)

which may be important for the cellular response to DNA damage

tissue-specific promoters and two polyA-addition sites

The active site residues of carboxypeptidases A and B are conserved in this protein

WFS1 Polyclonal Antibody, 20ul Cell Screening and Imaging Melanoma inhibitory activity (cartilage-derived retinoicThis gene encodes a transmembrane protein, which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta cell lines. Mutations in this gene are associated with Wolfram syndrome, also called DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness), an autosomal recessive disorder. The disease affects the brain and central nervous system.

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