Manic Fringe Polyclonal Antibody, 100ul Shakers The product of MED13 is

The product of MED13 is proposed to form a sub-complex with MED12

also known as lipocalins

This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response

RNA editing is predicted to alter the structure of the second intracellular loop

Manic Fringe Polyclonal Antibody, 100ul Shakers The product of MED13 isMFNG is a member of the fringe gene family which also includes radical and lunatic fringe genes. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose specific beta 1,3 N acetylglucosaminyltransferase activity that leads to elongation of O linked