UE2NL Rabbit Polyclonal Antibody, 50ul Peptide Modification Two alternative transcripts encoding different

Two alternative transcripts encoding different isoforms with distinct biological activity have been described

This gene encodes an endoplasmic reticulum membrane protein that is required for utilization of the mannose donor mannose-P-dolichol in the synthesis of lipid-linked oligosaccharides and glycosylphosphatidylinositols

This protein can form heteromultimers with two other potassium channel proteins

This protein is monoubiquinated in response to DNA damage

UE2NL Rabbit Polyclonal Antibody, 50ul Peptide Modification Two alternative transcripts encoding differentThis gene is intronless and encodes a member of the ubiquitin conjugating enzyme family. The protein product is 91% identical to ubiquitin conjugating enzyme E2N a multi exon gene product. This locus represents a polymorphic pseudogene where some individuals contain an allele that can encode a full length protein while others have a non functional allele containing a premature stop codon (reference SNP rs237520) that truncates the coding sequence.