Patched Polyclonal Antibody, 100ul Serological Pipets Activation of the receptor ultimately
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Patched Polyclonal Antibody, 100ul Serological Pipets Activation of the receptor ultimatelyPTCH1 (patched 1) encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of PTCH1 have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas,
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