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AFF4 Polyclonal Antibody, 50ul Monoclonal Antibody Preparation TBC1D10B functions as a GAP

SKU: 68186099115

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AFF4 Polyclonal Antibody, 50ul Monoclonal Antibody Preparation TBC1D10B functions as a GAPThe protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins(5; 11)(q31; q31q23).

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Description

TBC1D10B functions as a GAP for several proteins of the Rab family (Ishibashi et al

NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors

The PWWP2B gene is conserved in chimpanzee

fetal and neonatal tissues

AFF4 Polyclonal Antibody, 50ul Monoclonal Antibody Preparation TBC1D10B functions as a GAPThe protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins(5; 11)(q31; q31q23).

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