TIGD4 Polyclonal Antibody, 100ul Immune Cell Preparation and these and other mutations

and these and other mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD)

The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family| a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane

Multiple transcript variants encoding distinct isoforms have been identified for ACLY

Localizes to centrosomes

TIGD4 Polyclonal Antibody, 100ul Immune Cell Preparation and these and other mutationsThe protein encoded by this gene belongs to the tigger subfamily of the pogo superfamily of DNA mediated transposons in humans. These proteins are related to DNA transposons found in fungi and nematodes, and more distantly to the Tc1 and mariner transposases. They are also very similar to the major mammalian centromere protein B. The exact function of this gene is not known.