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PERM (84k| Cleaved-Ser155) Rabbit Polyclonal Antibody, 20ul Bacterial Expression Mutations in this gene are

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PERM (84k| Cleaved-Ser155) Rabbit Polyclonal Antibody, 20ul Bacterial Expression Mutations in this gene areMyeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils.

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Description

Mutations in this gene are associated with neurodegeneration with brain iron accumulation (NBIA)

and regulates expression of target genes containing retinoid response elements

it ensures efficient purification and clarity

Two transcript variants encoding different isoforms have been found for HSP90AA1

PERM (84k| Cleaved-Ser155) Rabbit Polyclonal Antibody, 20ul Bacterial Expression Mutations in this gene areMyeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils.

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