DOCK4 Rabbit Polyclonal Antibody, 100ul Vessels as well as in inducing

as well as in inducing apoptosis by modulating the expression of apoptotic and antiapoptotic proteins

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This gene encodes a member of the synaptic vesicle proteins 2 (SV2) family and major facilitator superfamily of proteins

Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia (PMID:18378094)

DOCK4 Rabbit Polyclonal Antibody, 100ul Vessels as well as in inducingThis gene is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR 1 (CZH 1) domain a DHR 2 (CZH 2) domain and an SH3 domain. This membrane associated cytoplasmic protein functions as a guanine nucleotide exchange factor and is involved in regulation of adherens junctions between cells. Mutations in this gene have been associated with ovarian prostate glioma and colorectal cancers. Alternatively spliced variants which