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GADD 45 Gamma Polyclonal Antibody, 50ul Plasma The paired box 4 gene

SKU: 69118176461

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GADD 45 Gamma Polyclonal Antibody, 50ul Plasma The paired box 4 geneGADD45G is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA damaging agents. Growth arrest and DNA damage inducible protein GADD45 gamma encoded by GADD45G responds to environmental stresses by mediating activation of the p38 JNK pathway via MTK1 MEKK4 kinase. The GADD45G is highly expressed in placenta.

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Description

The paired box 4 gene is involved in pancreatic islet development and mouse studies have demonstrated a role for this gene in differentiation of insulin-producing beta cells

C2orf40 (Chromosome 2 Open Reading Frame 40) is a Protein Coding gene

This gene is thought to be involved in CNS development

The function of this gene appears to be primarily to regulate expression of the TS locus both via the antisense transcript as well as through the encoded proteins

GADD 45 Gamma Polyclonal Antibody, 50ul Plasma The paired box 4 geneGADD45G is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA damaging agents. Growth arrest and DNA damage inducible protein GADD45 gamma encoded by GADD45G responds to environmental stresses by mediating activation of the p38 JNK pathway via MTK1 MEKK4 kinase. The GADD45G is highly expressed in placenta.

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