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E4BP4 Polyclonal Antibody, 100ul Deep Well Plates one encoding a secreted isoform

SKU: 69284678475

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E4BP4 Polyclonal Antibody, 100ul Deep Well Plates one encoding a secreted isoformNuclear factor, interleukin 3 regulated encoded by NFIL3 is a transcriptional regulator that binds as a homodimer to activating transcription factor (ATF) sites in many cellular and viral promoters. The encoded protein represses PER1 and PER2 expression and therefore plays a role in the regulation of circadian rhythm. Three transcript variants encoding the same protein have been found for NFIL3.

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Description

one encoding a secreted isoform and the others encoding nonsecreted isoforms

The encoded protein acts as a transcriptional repressor by binding to the non-coding RNA

Expression is slightly down-regulated by dexamethasone and slightly up-regulated by IL-10

PPP1R1B may serve as a therapeutic target for neurologic and psychiatric disorders

E4BP4 Polyclonal Antibody, 100ul Deep Well Plates one encoding a secreted isoformNuclear factor, interleukin 3 regulated encoded by NFIL3 is a transcriptional regulator that binds as a homodimer to activating transcription factor (ATF) sites in many cellular and viral promoters. The encoded protein represses PER1 and PER2 expression and therefore plays a role in the regulation of circadian rhythm. Three transcript variants encoding the same protein have been found for NFIL3.

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