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GRF-1(Phospho Tyr1105) Polyclonal Antibody, 100ul RNA Synthesis Overexpression of this gene is

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GRF-1(Phospho Tyr1105) Polyclonal Antibody, 100ul RNA Synthesis Overexpression of this gene isThe human glucocorticoid receptor DNA binding factor, which associates with the promoter region of the glucocorticoid receptor gene (hGR gene), is a repressor of glucocorticoid receptor transcription. The amino acid sequence deduced from the cDNA sequences show the presence of three sequence motifs characteristic of a zinc finger and one motif suggestive of a leucine zipper in which 1 cysteine is found instead of all leucines. The GRLF1 enhances the

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Description

Overexpression of this gene is seen in several cancers

proliferation and differentiation

and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells

Promotes mitochondrial fragmentation and influences mitochondrial localization

GRF-1(Phospho Tyr1105) Polyclonal Antibody, 100ul RNA Synthesis Overexpression of this gene isThe human glucocorticoid receptor DNA binding factor, which associates with the promoter region of the glucocorticoid receptor gene (hGR gene), is a repressor of glucocorticoid receptor transcription. The amino acid sequence deduced from the cDNA sequences show the presence of three sequence motifs characteristic of a zinc finger and one motif suggestive of a leucine zipper in which 1 cysteine is found instead of all leucines. The GRLF1 enhances the

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