DUS26 Polyclonal Antibody, 50ul Modification Enzymes Diseases associated with IGHG1 include

Diseases associated with IGHG1 include chronic lymphocytic leukemia and heavy chain deposition disease

In contrast to other MBD family members

C8 participates in the formation of the membrane attack complex (MAC) on bacterial cell membranes

Two variants| one protein-coding and the other not| have been found for this gene

DUS26 Polyclonal Antibody, 50ul Modification Enzymes Diseases associated with IGHG1 includeThis gene encodes a member of the tyrosine phosphatase family of proteins and exhibits dual specificity by dephosphorylating tyrosine as well as serine and threonine residues. This gene has been described as both a tumor suppressor and an oncogene depending on the cellular context. This protein may regulate neuronal proliferation and has been implicated in the progression of glioblastoma through its ability to dephosphorylate the p53 tumor suppressor.