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p53(Phospho Ser315) Polyclonal Antibody, 50ul Vortex Mixer Belongs to the CDC50/LEM3 family

SKU: 69574731291

4.9
USD162.00 USD202.00

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p53(Phospho Ser315) Polyclonal Antibody, 50ul Vortex Mixer Belongs to the CDC50/LEM3 familyThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

Belongs to the CDC50/LEM3 family

kidney or liver

BCAS2 was identified through differential display analysis as an mRNA species that was overexpressed in MCF7 and BT-20 breast cancer cell lines

This kinase binds to TRAF2 and stimulates NF-kappaB activity

p53(Phospho Ser315) Polyclonal Antibody, 50ul Vortex Mixer Belongs to the CDC50/LEM3 familyThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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