KRT34 Polyclonal Antibody, 20ul DNA Fragments The N-terminal nonkinase domain may

The N-terminal nonkinase domain may contain a regulatory domain

The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections

Multiple alternatively spliced variants have been found in normal and cancerous tissues

Mutations in this gene have been associated with microencephaly| cortical malformations| and mental retardation

KRT34 Polyclonal Antibody, 20ul DNA Fragments The N-terminal nonkinase domain mayThe protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12 q21 and have the same direction of transcription.