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Caspase-8 Polyclonal Antibody, 20ul[BT-AP07124] Plasmid Preparation NF-kappa-B moves to the nucleus

SKU: 70170859731

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Caspase-8 Polyclonal Antibody, 20ul[BT-AP07124] Plasmid Preparation NF-kappa-B moves to the nucleusThis gene encodes a member of the cysteine aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large

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Description

NF-kappa-B moves to the nucleus and activates transcription of specific genes

NFKB1/p50 interacts with NFKBIE

where it binds OGF and is translocated into the nucleus

An important paralog of this gene is BARX2

Caspase-8 Polyclonal Antibody, 20ul[BT-AP07124] Plasmid Preparation NF-kappa-B moves to the nucleusThis gene encodes a member of the cysteine aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large

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