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CD56 Polyclonal Antibody, 100ul[BT-AP02459] Lentiviral Packaging The protein encoded by DOK2

SKU: 7039794477

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CD56 Polyclonal Antibody, 100ul[BT-AP02459] Lentiviral Packaging The protein encoded by DOK2KRT10 encodes a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in KRT10 are associated with epidermolytic hyperkeratosis. This gene is located within a cluster of

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Description

The protein encoded by DOK2 (docking protein 2)is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase

and appears to be the principal fatty acid transporter in enterocytes

The chromosomal rearrangements are the most common genetic alterations in this gene| which result in creation of multiple fusion genes in tumourigenesis| including ALK (chromosome 2)/EML4 (chromosome 2)| ALK/RANBP2 (chromosome 2)| ALK/ATIC (chromosome 2)| ALK/TFG (chromosome 3)| ALK/NPM1 (chromosome 5)| ALK/SQSTM1 (chromosome

The protein encoded by this gene is the gamma component of fibrinogen

CD56 Polyclonal Antibody, 100ul[BT-AP02459] Lentiviral Packaging The protein encoded by DOK2KRT10 encodes a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in KRT10 are associated with epidermolytic hyperkeratosis. This gene is located within a cluster of

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