EMAL4 Rabbit Polyclonal Antibody, 20ul ADME CLPTM1 (Cleft Lip And Palate

CLPTM1 (Cleft Lip And Palate Associated Transmembrane Protein 1) is a Protein Coding gene

It encodes the gamma-aminobutyric acid (GABA) A receptor which is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system

This receptor is capable of stimulating T-cell proliferation in the presence of CD3 signaling

and thus may mediate the signaling processes that lead to the activation of JAK1

EMAL4 Rabbit Polyclonal Antibody, 20ul ADME CLPTM1 (Cleft Lip And PalateThis gene is a member of the echinoderm microtubule associated protein like family. The encoded WD repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene which generates EML4 ALK fusion transcripts is one of the primary mutations associated with non small cell lung cancer. Alternative splicing of this gene results in two transcript variants.