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Phospho-AP-1 (T231) Polyclonal Antibody, 100ul Electronic Pipette the N-terminal region contains a

SKU: 70476518870

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Phospho-AP-1 (T231) Polyclonal Antibody, 100ul Electronic Pipette the N-terminal region contains aJUN is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32 p31, a chromosomal region involved in both translocations and deletions in human malignancies.

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Description

the N-terminal region contains a polyglutamine tract of 14-31 residues that can be expanded in the pathogenic state to 32-200 residues

Defects in this gene are a cause of long QT syndrome type 10 (LQT10)

and also a C-terminal domain which resembles enoyl-CoA-isomerase

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Phospho-AP-1 (T231) Polyclonal Antibody, 100ul Electronic Pipette the N-terminal region contains aJUN is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32 p31, a chromosomal region involved in both translocations and deletions in human malignancies.

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