NUDT5 Rabbit Polyclonal Antibody, 20ul Cell Function Analysis Reduced expression and rearrangement of

Reduced expression and rearrangement of this gene have been detected in various cancers

which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors

The protein encoded by this gene is a member of the X11 protein family

including Glanzmann thrombasthenia

NUDT5 Rabbit Polyclonal Antibody, 20ul Cell Function Analysis Reduced expression and rearrangement ofThis gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates including ADP ribose (ADPR) and 8 oxoGua containing 8 oxo dADP and 8 oxo dGDP. Protein bound ADP ribose can be hazardous to the cell because it can modify some amino acid residues resulting in the inhibition of ATP activated potassium channels. 8 oxoGua is an oxidized form of