Chk1(Phospho Ser345) Polyclonal Antibody, 100ul Lysosome The function of this gene

The function of this gene and its encoded protein is not known

RYR2 (ryanodine receptor 2) encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum

This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex

and expansion of the number of repeats to 45-66 increases the length of the polyglutamine string and is associated with spinocerebellar ataxia 17

Chk1(Phospho Ser345) Polyclonal Antibody, 100ul Lysosome The function of this geneThe protein encoded by this gene belongs to the Ser Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells