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NOTCH1 (Cleaved-Val1711) Rabbit Polyclonal Antibody, 100ul Subcellular Fractions This kinase has been shown

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NOTCH1 (Cleaved-Val1711) Rabbit Polyclonal Antibody, 100ul Subcellular Fractions This kinase has been showndisease: Defects in NOTCH1 are a cause of aortic valve disease

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Description

This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1

The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication

This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family

The encoded protein interacts with IRS1 protein| suggesting a role in regulating insulin sensitivity

NOTCH1 (Cleaved-Val1711) Rabbit Polyclonal Antibody, 100ul Subcellular Fractions This kinase has been showndisease: Defects in NOTCH1 are a cause of aortic valve disease

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