Rat Insulin-like Growth Factor Binding Protein 1, IGFBP-1 ELISA Kit, 96T Drug Development and Evaluation thus cyclin dependent kinase inhibitor

thus cyclin dependent kinase inhibitor 2B functions as a cell growth regulator that controls cell cycle G1 progression

Found in a complex with XPO7

Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found

regulates the level and transcriptional activity of nuclear CTNNB1/beta-catenin (PubMed: 17229088)

Rat Insulin-like Growth Factor Binding Protein 1, IGFBP-1 ELISA Kit, 96T Drug Development and Evaluation thus cyclin dependent kinase inhibitorIGF binding proteins prolong the half life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration (By similarity).