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TDH Rabbit Polyclonal Antibody, 100ul Thermo Mix This enzyme plays a central

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TDH Rabbit Polyclonal Antibody, 100ul Thermo Mix This enzyme plays a centralThis gene appears to be an evolving pseudogene of L threonine 3 dehydrogenase (TDH). In both prokaryotes and eukaryotes TDH catalyzes the first of two steps in one of two L threonine degradation pathways. However in human the single gene with sequence similarity to TDH is not capable of encoding a functional TDH protein; the predicted protein lacks most of the C terminus and parts of the NAD+ binding motif when compared to other species' TDH proteins.

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Description

This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway

Mutations in this gene are associated with Ehlers-Danlos syndrome| types I and II

It also functions as a repressor of NF-kappa-B by promoting ubiquitination of the NF-kappa-B subunit RELA in a HAT-independent manner

MIM 602276)-containing (ATAC) histone acetyltransferase complex

TDH Rabbit Polyclonal Antibody, 100ul Thermo Mix This enzyme plays a centralThis gene appears to be an evolving pseudogene of L threonine 3 dehydrogenase (TDH). In both prokaryotes and eukaryotes TDH catalyzes the first of two steps in one of two L threonine degradation pathways. However in human the single gene with sequence similarity to TDH is not capable of encoding a functional TDH protein; the predicted protein lacks most of the C terminus and parts of the NAD+ binding motif when compared to other species' TDH proteins.

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