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MDM2 Polyclonal Antibody, 50ul[BT-AP05300] Vacuum Aspirator The protein encoded by this

SKU: 71914629149

4.6
SEK142.00 SEK183.00

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MDM2 Polyclonal Antibody, 50ul[BT-AP05300] Vacuum Aspirator The protein encoded by thisMDM2 encodes a nuclear localized E3 ubiquitin ligase. E3 ubiquitin protein ligase Mdm2 can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. MDM2 is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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Description

The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK)

The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism

tissue specificity:In brain

PIAS1 encodes a member of the protein inhibitor of activated STAT (PIAS) family

MDM2 Polyclonal Antibody, 50ul[BT-AP05300] Vacuum Aspirator The protein encoded by thisMDM2 encodes a nuclear localized E3 ubiquitin ligase. E3 ubiquitin protein ligase Mdm2 can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. MDM2 is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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