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Phospho-Btk (Y223) Polyclonal Antibody, 100ul Organelle Studies maps to chromosome 6p21

SKU: 72110798528

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Phospho-Btk (Y223) Polyclonal Antibody, 100ul Organelle Studies maps to chromosome 6p21Bruton tyrosine kinase encoded by BTK plays a crucial role in B cell development. Mutations in BTK cause X linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Description

maps to chromosome 6p21

The Reg gene family is a multigene family grouped into four subclasses

The product of this gene belongs to the B' family

Reciprocal translocations between chromosomes 22 and 17

Phospho-Btk (Y223) Polyclonal Antibody, 100ul Organelle Studies maps to chromosome 6p21Bruton tyrosine kinase encoded by BTK plays a crucial role in B cell development. Mutations in BTK cause X linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.

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